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When constructing a research question, the PICO format is widely used for questions of therapy.
Frame your question to include:
|P (patient/problem)||hospital infection|
|C (comparison)||no handwashing; other solution; masks|
|O (outcome of interest)||reduced infection|
Including the PICO elements in your question will help you to approach the literature search in a focused way as a first step to gathering evidence.
Link to clinical question PICO worksheet (Dartmouth Biomedical Libraries)
- Link to worksheet for constructing PICO question online (Duke University Medical Center)
The sample searches below demonstrate PICO questions and a search strategy.